Acne is one of the most common and distressing symptoms of PCOS, affecting approximately 49% of women with the condition. The characteristic PCOS acne location along the chin and jawline is not coincidental: it is a direct expression of androgen excess on the sebaceous glands. A 2025 meta-analysis including 95 studies confirmed that acne vulgaris has a pooled prevalence of 49% in women with PCOS, making it one of the most frequent comorbidities of the syndrome. In PCOS acne, the chin and jawline are particularly androgen-sensitive areas because the oil-producing (sebaceous) glands in this region have a higher density of…